Dear Colleagues: We are pleased to announce that a revised version of the NSF Grants.gov Application Guide has been issued. Information about FastLane system registration has been removed and replaced with guidance for registering in Research.gov. Editorial changes have also been made to either clarify or enhance the intended meaning of a sentence or section or to ensure consistency with data contained in NSF systems or other NSF policy documents. The new NSF Grants.gov Application Guide will be effective for proposals submitted, or due, on or after January 29, 2018. If you have any questions regarding these changes, please contact the Policy Office on (703) 292-8243 or by e-mail to firstname.lastname@example.org. For technical questions relating to Grants.gov, please contact Grants.gov directly at 1-800-518-4726 or email@example.com.