Dr. Sharifa Love-Rutledge

Assistant Professor, Chemistry Department

Biography

Dr. Love-Rutledge’s research interests are in the areas of diabetes and insulin resistance. Research in her laboratory focuses on two specific goals i) identification and characterization of early targetable signals related to the dysfunction of insulin secreting β cells and ii) understanding the effect proteins, like FAT10, a Type 1 diabetes susceptibility gene, have on β cells and insulin sensitive tissues such as (or including) liver, muscle, and fat. In the laboratories efforts to solve complex problems, identify important disease pathways and isolate biomarkers for disease status during the onset of diabetes, we utilize a combination of state-of-the-art biochemistry, analytical chemistry, and molecular biology methodology to achieve our research goals.

Visit Sharifa Love-Rutledge's research webpage


Education

  • Postdoctoral Research Associate, Department of Physiology, Michigan State University, 2014-2017
  • Ph.D., Biochemistry, The University of Alabama, 2014
  • B.S., Chemistry, Tougaloo College, 2008

Publications

  • Love ST, Di Bona KR, Sinha SH, McAdory D, Skinner BR, Rasco JF, & Vincent JB. Urinary Chromium Excretion in Response to an Insulin Challenge Is Not a Biomarker for Chromium Status Biological Trace Element Research 2013, 152(1):57-65
  • Staniek H, Rhodes NR, Di Bona KR, Deng G, Love ST, Pledger LA, Blount J, Gomberg E, Grappe F, Cernosek C, Peoples B, Rasco JF, Krejpcio Z, & Vincent JB. Comparison of Tissue Metal Concentrations in Zucker Lean, Zucker Obese, and Zucker Diabetic Fatty Rats and the Effects of Chromium Supplementation on Tissue Metal Concentrations Biological Trace Element Research 2013, 151(3):373-83
  • Vincent JB, Love S. The Need for Combined Inorganic, Biochemical, and Nutritional Studies of Chromium (III) Chemistry & Biodiversity 2012, 9(9):1923-41
  • Vincent JB, Love S. The binding and transport of alternative metals by transferrin. Biochimica Biophysica Acta -General Subjects 2012, 1820(3):362-78
  • Di Bona KR, Love S, Rhodes NR, McAdory D, Sinha SH, Kern N, Kent J, Strickland J, Wilson A, Beaird J, Ramage J, Rasco JF & Vincent JB. Chromium is not an essential trace element for mammals: Effects of a “low-chromium” diet. Journal of Biological Inorganic Chemistry. 2010, 16(3):381-90.
  • Rhodes NR, McAdory D, Love S, Di Bona KR, Chen Y, Ansorge K, Hira J, Kern N, Kent J, Lara P, Rasco JF & Vincent JB. Urinary chromium loss associated with diabetes is offset by increases in absorption. Journal of Inorganic Biochemistry. 2010, 104(7): 790-97.