Jerome Baudry, Ph.D.

Mrs. Pei-Ling Chan Chair & Professor, Biological Sciences


301 Sparkman Drive
Shelby Center
Room 302K
Huntsville, AL 35899
Campus Map



Professor Jerome Baudry is the Mrs. Pei-Ling Chan Professor of Biological Sciences, University of Alabama, Huntsville; Department of Biological Sciences. Dr. Baudry obtained his Ph.D. in Molecular Biophysics with the highest Honors from the University of Paris, UPMC/Sorbonne Universities, France. He subsequently joined the group of Klaus Schulten at the University of Illinois at Urbana-Champaign as a post-doc. After his post-doctoral work, Dr. Baudry worked in the pharmaceutical industry as a Research Scientist, and then accepted a Senior Research Scientist position back in Illinois on a non-tenure track research faculty position. Dr. Baudry joined the University of Tennessee, Knoxville and the UT/ORNL Center for Molecular Biophysics as a tenure track Assistant Professor in 2008. In 2014, he was promoted to Associate Professor with tenure. In August 2017, Dr. Baudry joined UAH as the Mrs. Pei-Ling Chan Professor. At UAH, Dr. Baudry's group develops and applies methods and protocols for computational drug discovery, both on small-molecules and biologicals, within academic, national laboratories and industrial collaborations.

Curriculum Vitae

Research Website


  • Ph.D., Molecular Biophysics, University of Paris UPMC - Sorbonne Universités, Paris, France, Highest Honors ("Très Honorable avec Félicitations")


  • Drug discovery
  • Computational biology
  • Molecular biophysics
  • Pharmaceuticals
  • Molecular modeling

Recent Publications

  • Structure based virtual screening identifies small molecule effectors for the sialoglycan binding protein HsaR Agarwal, BA Bensing, D Mi, PN Vinson, J Baudry, TM Iverson, JC Smith Biochemical Journal 477 (19), 3695-3707, 2020

  • Supercomputer-based ensemble docking drug discovery pipeline with application to Covid-19 A Acharya, R Agarwal, M Baker, J Baudry, D Bhowmik, S Boehm, et al. ChemRxiv 2020

  • Structure-based group A streptococcal vaccine design: Helical wheel homology predicts antibody cross-reactivity among streptococcal M protein–derived peptides MP Aranha, TA Penfound, JA Spencer, R Agarwal, J Baudry, JB Dale, ...Journal of Biological Chemistry 295 (12), 3826-3836, 2020

  • Sequential dynamics of Stearoyl-CoA Desaturase-1 (SCD1)/ligand binding and unbinding mechanism: A computational study A Petroff, RL Weir, CR Yates, JD Ng, J Baudry, bioRxiv, 2020

  • High Performance Computing Prediction of Potential Natural Product Inhibitors of SARS-CoV-2 Key Targets. K. Byler, J Landman, J Baudry ChemRxiv 2020

  • Structure based virtual screening identifies novel competitive inhibitors for the sialoglycan binding protein HsaR Agarwal, BA Bensing, D Mi, PN Vinson, J Baudry, TM Iverson, JC Smith bioRxiv, 2020

  • Novel K-Means Clustering-based Undersampling and Feature Selection for Drug Discovery Applications VS Akondi, V Menon, J Baudry, J Whittle 2019 IEEE International Conference on Bioinformatics and Biomedicine, 2019

  • Ligand-Dependent Sodium Ion Dynamics within the A2A Adenosine Receptor: A Molecular Dynamics StudyX Hu, MD Smith, BM Humphreys, AT Green, JM Parks, JY Baudry, et al. The Journal of Physical Chemistry B 123 (38), 7947-7954, 2019

  • Interdimer zipping in the chemoreceptor signaling domain revealed by molecular dynamics simulations MG Petukh, DR Ortega, J Baudry, IB Zhulin

  • Ensemble Docking in Drug Discovery: How Many Protein Configurations from Molecular Dynamics Simulations Are Needed to Reproduce Known Ligand Binding? W Evangelista, SR Ellingson, JC Smith, JY Baudry The Journal of Physical Chemistry B