Dr. Surangi Jayawardena

Assistant Professor, Chemistry


301 Sparkman Drive
Materials Science Building
Room 305
Huntsville, AL 35899
Campus Map



Dr. Jayawardena's research focuses on theranostic nanostructures capable of providing both therapeutic and diagnostics in-vivo and in-vitro environments for infectious diseases. Design of theses theranostic systems involve synthesis of nanoparticle cores with diagnostic aids such as fluorescence, magnetic resonance, along with surface modification chemistry to modify particle surface to carry biorecognition molecules, small molecule drugs and biocompatible polymers for targeted therapy. Her laboratory utilizes synthetic analytical and material characterization techniques to design theranostic systems, these include small molecule synthesis for bioconjugation, synthesis of various inorganic and organic nanomaterial and application in ex-vivo, in-vitro and in-vivo settings.

Curriculum Vitae

Personal Website


  • Ph.D., Chemistry. University of Massachusetts, Lowell 2014
  • B. Sc, Chemistry, University of Colombo, Colombo, Sri Lanka 2008

Honors & Awards

  • 2020 Boost Idea Competition - February 2020
  • iCorps - IgniteHSV Award, November 2019 - University of Alabama Huntsville
  • Individual Investigator Distinguished Award May 2018 - University of Alabama Huntsville
  • Charger Innovation Award, February 2018 - University of Alabama Huntsville
  • New Faculty Research Award, August 2017 - University of Alabama Huntsville
  • Tripathy Memorial Summer Graduate Fellowship, June 2014 - University of Massachusetts Lowell
  • Outstanding Graduate Research Award, August 2014 - University of Massachusetts Lowel


  • Theranostic nanostructures

Recent Publications

  • Rathnayake, K.; Patel, U.; Pham, C.; McAlpin, A.; Budisalich,.; Jayawardena, S. N. Targeted Delivery of Antibiotic Therapy to Inhibit Pseudomonas aeruginosa Using Lipid-Coated Mesoporous Silica Core Shell Nanoassembly. ACS Applied Bio Materials 2020.

  • McHugh, K. J.; Jing, L.; Severt, S. Y.; Cruz, M.; Sarmadi, M.; Jayawardena, H. S. N.; Perkinson, C. F.; Larusson, F.; Rose, S.; Tomasic, S.; Graf, T.; Tzeng, S. Y.; Sugarman, J. L.; Vlasic, D.; Peters, M.; Peterson, N.; Wood, L.; Tang, W.; Yeom, J.; Collins, J.; Welkhoff, P. A.; Karchin, A.; Tse, M.; Gao, M.; Bawendi, M. G.; Langer, R.; Jaklenec, A. Biocompatible near-infrared quantum dots delivered to the skin by microneedle patches record vaccination. Sci. Transl. Med. 2019, 11, 7162.

  • Ferber, S.; Behrens, A. M.; McHugh, K. J.; Rosenberg, E. M.; Linehan, A. R.; Sugarman, J. L.; Jayawardena, H. S. N.; Langer, R.; Jaklenec, A. Evaporative Cooling Hydrogel Packaging for Storing Biologics Outside of the Cold Chain. Adv. Healthc. Mater. 2018, 7, 1800220.

  • Petgna, L., Jayawardana, H. Surangi, N.: Knowledge-Driven Vaccine Systems Engineering. The Thirteenth International Conference on Systems. 2018,12-17.

  • McHugh, K., Jing, L., Berhens, A., Jayawardena, H. Surangi N., Tang., W. Langer, S. R., Jaklenec, A. Biocompatible Semiconductor Quantum Dots as Cancer Imaging Agents. Adv. Mater. 2018, 30, 1706356.

  • Sundhoro, M.; Park, J.; Jayawardana, K. W.; Chen, X.; Jayawardena, H. S. N.; Yan, M. Poly(HEMA-co-HEMA-PFPA): Synthesis and preparation of stable micelles encapsulating imaging nanoparticles. J. Colloid Interface Sci. 2017, 500, 1-8.

  • Chen, X.; Wu, B.; Jayawardana, K. W.; Hao, N.; Jayawardena, H. S. N.; Langer R.; Jaklenec, A.; Yan, M. Magnetic multivalent trehalose glycopolymer nanoparticles for the detection of mycobacteria, Adv. Healthc. Mater. 2016, 5, 2007-2012.

  • Zhang, Y.; Jayawardena, H. S. N.; Yan, M.; Ramstrom, O. Enzyme classification using complex dynamic hemithioacetal systems. Chem. Commun. 2016, 52, 5053-5056.

  • Sundhoro, M.; Wang, H.; Boiko, S. T.; Chen, X.; Jayawardena, H. S. N.; Park, J.; Yan, M. Fabrication of carbohydrate microarrays on a poly (2-hydroxyethyl methacrylate)-based photoactivesubstrate. Organic & biomolecular chemistry 2016, 14, 1124-1130.

  • Park, J.; Jaywawadena, H. S. N.; Chen, X.; Jayawadana, K.; Sundhoro, M.; Ada, E.; Yan, M. A General Method for the Fabrication of Graphene-Nanoparticle Hybrid Material. (2015)Chem. Commun. 2015, 51, 2882–2885