"Gene regulation through the control of ribosome movement"

Friday, March 19, 2021Last RepeatFirst Repeat The event started -183 days ago

1:00 PM 2:00 PM

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Matthew S. Sachs

Department of Biology, Texas A&M University

"Gene regulation through the control of ribosome movement"

Summary: A special class of conserved upstream open reading frames (uORFs) encodes peptides that stall protein synthesis in response to the presence of small metabolites. These nascent regulatory peptides act within the ribosome tunnel to arrest translation; by doing so, they can control the production of enzymes important in metabolism. We discuss the functions of such uORFs in the model filamentous fungus Neurospora crassa and structural analyses of the N. crassa ribosome at near-atomic resolution.

ribosome

Email biology.chair@uah.edu for more meeting details.


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Category
Conference/Lecture
department
Biological Science, College of Science
Audience
Students, Faculty and Staff, Alumni

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