Ifedayo Victor Ogungbe, Ph.D.

Associate Professor, Chemistry

Contact

301 Sparkman Drive
Materials Science Building
Room 211
Huntsville, AL 35899
Campus Map

256.824.2923
victor.ogungbe@uah.edu

Biography

Curriculum Vitae

Education

  • Ph.D., Biotechnology Science and Engineering, The University of Alabama in Huntsville, 2011
  • M.S., Chemistry, The University of Alabama in Huntsville, 2009

Expertise

  • Drug discovery for infectious diseases, cancer, and crop protection; Drug target identification; chemical proteomics; and lipidomics.

Recent Publications

  • Nyamwihura RJ, Ogungbe IV. The pinene scaffold: its occurrence, chemistry, synthetic utility, and pharmacological importance. RSC advances. 2022, 12, 11346-11375.

  • Nyamwihura RJ, Zhang H, Collins JT, Crown O, Ogungbe IV. Nopol-Based Quinoline Derivatives as Antiplasmodial Agents. Molecules. 2021, 26: 1008.  PMC7917639

  • Santos CC, Zhang H, Batista MM, de Oliveira GM, Demarque KC, da Silva-Gomes NL, Moreira OC, Ogungbe IV, Soeiro MD. In Vitro and In Vivo Evaluation of an Adamantyl-Based Phenyl Sulfonyl Acetamide against Cutaneous Leishmaniasis Models of Leishmania amazonensis. Antimicrobial agents and chemotherapy. 2020, 64: e01188-20. 

  • Zhang H, Harmon M, Radoshitzky Sheli, Soloveva V, Kane Chris, Duplantier Allen, Ogungbe, IV. Vinyl Sulfone-Based Inhibitors of Non-Structural Protein 2 Block the Replication of Venezuelan Equine Encephalitis Virus. ACS Med. Chem. Letters, 2020, 11, 2139–2145

  • Zhang H, Collins J, Nyamwihura R, Crown O, Ajayi O, Ogungbe IV. Vinyl Sulfone-based Inhibitors of Trypanosomal Cysteine Protease Rhodesain with Improved Antitrypanosomal Activities. Bioorganic & Medicinal Chemistry Letters. 2020, 127217.

  • Zhang H, Collins J, Nyamwihura R, Ware S, Kaiser M, Ogungbe IV. Discovery of a Quinoline-Based Phenyl Sulfone Derivative as an Antitrypanosomal Agent. Bioorganic and Medicinal Chemistry Letters 2018, 28: 1647-1651. PMC5912169

  • Byler KG, Collins JT, Ogungbe IV, Setzer WN. Alphavirus protease inhibitors from natural sources: A homology modeling and molecular docking investigation. Comput Biol Chem. 2016, 64:163-184. PMID: 27387412.

  • Jefferson T, McShan D, Warfield J, Ogungbe IV. Screening and Identification of Inhibitors of Trypanosoma brucei Cathepsin L with Antitrypanosomal Activity. Chemical Biology & Drug Design 2016, 58: 154-158. PMC4715686

  • McShan D, Kathman S, Lowe B, Xu Z, Zhan J, Statsyuk A, Ogungbe IV. Identification of non-peptidic cysteine reactive fragments as inhibitors of cysteine protease rhodesain. Bioorganic & Medicinal Chemistry Letters 2015, 25: 4509-4512. PMC4592840

  • Kaul TK, Reis Rodrigues P, Ogungbe IV, Kapahi P, Gill MS. Bacterial fatty acids enhance recovery from the dauer larva in Caenorhabditis elegans. PLoS One. 2014: 9(1):e86979. PMCID: PMC3901721