Ifedayo Victor Ogungbe, Ph.D.

Associate Professor, Chemistry

Contact

301 Sparkman Drive
Materials Science Building
Room 211
Huntsville, AL 35899
Campus Map

256.824.2923
victor.ogungbe@uah.edu

Biography

Curriculum Vitae

Education

  • Ph.D., Biotechnology Science and Engineering, The University of Alabama in Huntsville, 2011
  • M.S., Chemistry, The University of Alabama in Huntsville, 2009

Expertise

  • Drug discovery for infectious diseases, cancer, and crop protection; Drug target identification; chemical proteomics; and lipidomics.

Recent Publications

  • Metibemu DS, Adeyinka OS, Falode J, Crown O, Ogungbe IV. Inhibitors of the Structural and Nonstructural Proteins of Alphaviruses. ACS infectious diseases. 2024, 10, 2507-2524.

  • Ajayi O, Metibemu DS, Crown O, Adeyinka OS, Kaiser M, Shoji N, Silva M, Rodriguez A, Ogungbe IV. Discovery of an orally active nitrothiophene-based antitrypanosomal agent. European Journal of Medicinal Chemistry. 263, 115954.

  • Kim PY, Kim AY, Newman JJ, Cella E, Bishop TC, Huwe PJ, Uchakina ON, McKallip RJ, Mack VL, Hill MP, Ogungbe IV. A collaborative approach to improving representation in viral genomic surveillance. PLOS Global Public Health. 2023, 3, e0001935.

  • Boghdeh NA, McGraw B, Barrera MD, Anderson C, Baha H, Risner KH, Ogungbe IV, Alem F, Narayanan A. Inhibitors of the ubiquitin-mediated signaling pathway exhibit broad-spectrum antiviral activities against New World alphaviruses. Viruses. 2023, 15, 655.

  • Adeyinka OS, Tabassum B, Koloko BL, Ogungbe IV. Enhancing the quality of staple food crops through CRISPR/Cas-mediated site-directed mutagenesis. Planta. 2023, 257, 78.

  • Nyamwihura RJ, Ogungbe IV. The pinene scaffold: its occurrence, chemistry, synthetic utility, and pharmacological importance. RSC advances. 2022, 12, 11346-11375.

  • Nyamwihura RJ, Zhang H, Collins JT, Crown O, Ogungbe IV. Nopol-Based Quinoline Derivatives as Antiplasmodial Agents. Molecules. 2021, 26: 1008.  PMC7917639

  • Santos CC, Zhang H, Batista MM, de Oliveira GM, Demarque KC, da Silva-Gomes NL, Moreira OC, Ogungbe IV, Soeiro MD. In Vitro and In Vivo Evaluation of an Adamantyl-Based Phenyl Sulfonyl Acetamide against Cutaneous Leishmaniasis Models of Leishmania amazonensis. Antimicrobial Agents and Chemotherapy. 2020, 64: e01188-20. 

  • Zhang H, Harmon M, Radoshitzky Sheli, Soloveva V, Kane Chris, Duplantier Allen, Ogungbe, IV. Vinyl Sulfone-Based Inhibitors of Non-Structural Protein 2 Block the Replication of Venezuelan Equine Encephalitis Virus. ACS Med. Chem. Letters, 2020, 11, 2139–2145

  • Zhang H, Collins J, Nyamwihura R, Crown O, Ajayi O, Ogungbe IV. Vinyl Sulfone-based Inhibitors of Trypanosomal Cysteine Protease Rhodesain with Improved Antitrypanosomal Activities. Bioorganic & Medicinal Chemistry Letters. 2020, 127217.