Associate Professor, Chemistry
Adjunct Professor, Materials Science
Office: MSB 139
- Morehouse College, I.B.S. Chemistry and Physics, 1991
- Louisiana State University, Ph.D. Analytical Chemistry, 2000.
- Assistant Professor, UAHuntsville, 2004 -
Dr. Waddell's research is in the area of near infrared time-resolved fluorescence. Following the receipt of his doctorate, Dr. Waddell completed a National Research Council Post-Doctoral Fellowship at the National Institute of Standards and Technology in Gaithersburg, MD where he became interested in the laser ablation of polymer substrates and its application in microfluidic (lab-on-a-chip) devices. Dr. Waddell is a member of the Biotechnology and Materials Science Faculty. (vita.pdf)
Laser Ablation and Surface Modification of Polymer Substrates for the Fabrication of Microfluidic Devices Micro total analytical systems (m-TAS) are rapidly emerging as a means to perform rapid, chemical analysis on small platforms that greatly reduce time and space requirements. For example, researchers have performed the polymerase chain reaction, oligonucleotide hybridization, chemical warfare agent identification, and DNA sequencing in m-TAS. Traditionally, these systems have been fabricated in glass substrates by chemical etching. Recently, there has been increased interest in fabricating m-TAS in polymer substrates due to reduced costs and amenability to multiple environments. One of the methods by which these systems may be fabricated in polymer substrates is by laser ablation. This technique utilizes the output of a pulsed laser to ablate microfluidic channels in polymer substrates. We are in the beginning stages of a research program that explores the use of UV laser ablation of polymers and its application towards m-TAS and sensor development.
Here is a short pdf of my ten minute PowerPoint. The blue box is a video of micromachining performed at NIST during my postdoc.
UV Laser Micromachining of Polymers for Microfluidic Applications, Emanuel Waddell, Laurie E. Locascio, and Gary W. Kramer, Journal of the Association for Laboratory Automation, 2002, 7(1), 78-82
Control of Electroosmotic Flow in Laser Ablated and Chemically Modified Hot Imprinted Poly(ethylene terephthalate glycol) Microchannels, Alyssa C. Henry, Emanuel Waddell, Rubina Shreiner, and Laurie E. Locascio, Electrophoresis, 2002, 23(5), 791-798.
Surface Characterization of Laser Ablated Polymers Used for Microfluidics, D.L. Pugmire, E.A. Waddell, R. Haasch, M.J. Tarlov, and L.E. Locascio, Analytical Chemistry, 2002, 74(4), 871-878.
Chemical Mapping of Hot-Embossed and UV-laser-ablated Microchannels in Poly(methyl methacrylate) using Carboxylate Specific Fluorescent Probes. Timothy J. Johnson, Emanuel A. Waddell, Gary W. Kramer, Laurie E. Locascio, Applied Surface Science, 2001, 181, 149-159.