William N. Setzer

setzer w

Department of Chemistry
Professor, Organic Chemistry

Adjunct Professor, Biological Sciences

Office: MSB 115
Phone: 256.824.6519
Fax: 256.824.6349
Email: wsetzer@chemistry.uah.edu

Résumé

Research Interests

My current research interests are concerned with secondary metabolites of higher plants; biomedicinal aspects of biologically active phytochemicals and chemical ecology.

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Selected Publications

"Hesperidin: A promising anticancer agent from nature." Devi, K.P..; Rajavel, T.; Nabavi, S.F.; Setzer, W.N.; Ahmadi, A.; Mansouri, K.; Nabavi, S.M. Industrial Crops and Products, 2015, 76, 582-589.

"Composition and bioactivities of an (E)-β-farnesene chemotype of chamomile (Matricaria chamomilla L.) essential oil from Nepal." Satyal, P.; Shrestha, S.; Setzer, W.N. Natural Product Communications, 2015, 10(8), 1453-1457.

"Composition and bioactivity of the essential oil of Tanacetum parthenium from a wild population growing in Tajikistan." Sharopov, F.S.; Setzer, W.N.; Isupov S.J., Wink, M. American Journal of Essential Oils and Natural Products, 2015, 2(4), 32-34.

"Antileishmanial activities of compounds isolated from Sassafras albidum." Pulivarthy, D.; Steinberg, K.M.; Monzote, L.; Piñón, A.; Setzer, W.N. Natural Product Communications, 2015, 10(7), 1229-1230.

"Chemical composition of Nardostachys grandiflora rhizome oil from Nepal – A contribution to the chemotaxonomy of Nardostachys." Satyal, P.; Chhetri, B.; Dosoky, N.S.; Poudel, A.; Setzer, W.N. Natural Product Communications, 2015, 10(6), 1067-1070.

"A survey of chemical compositions and biological activities of Yemeni aromatic medicinal plants." Chhetri, B.K.; Ali, N.A.A.; Setzer, W.N. Medicines, 2015, 2(2), 67-92.

"Essential oil composition of Artemisia abyssinica from three habitats in Yemen." Chhetri, B.K.; Al-Sokari, S.S.; Setzer, W.N.; Ali, N.A.A. American Journal of Essential Oils and Natural Products, 2015, 2(3), 28-30.

"Essential oil constituents of zira (Bunium persicum [Boiss.] B. Fedtsch.) from Tajikistan." Sharopov, F.S.; Kukaniev, M.A.; Zhang, H.; Setzer, W.N. American Journal of Essential Oils and Natural Products, 2015, 2(3), 24-27.

"Composition and bioactivities of the leaf essential oil of Ficus religiosa Linn." Poudel, A.; Satyal, P.; Setzer, W.N. American Journal of Essential Oils and Natural Products, 2015, 2(3), 16-17.

"A molecular docking study of phytochemical estrogen mimics from dietary herbal supplements." Powers, C.N.; Setzer, W.N. In Silico Pharmacotherapy, 2015, 3, 4 [DOI 10.1186/s40203-015-0008-z].

"Combinations of ascaridole, carvacrol, and caryophyllene oxide against Leishmania." Pastor, J.; García, M.; Steinbauer, S.; Setzer, W.N.; Scull, R.; Gille, L.; Monzote, L. Acta Tropica, 2015, 145, 31-38.

"Chemical composition, antifungal and antibacterial activities of essential oil from Lallemantia royleana (Benth. in Wall.) Benth." Rad, J.S.; Alfatemi, S.M.H.; Rad, M.S.; Setzer, W.N. Journal of Food Safety, 2015, 35, 19-25.

"Aromatic medicinal plants from Tajikistan (Central Asia)." Sharopov, F.S.; Zhang, H.; Wink, M.; Setzer, W.N. Medicines, 2015, 2, 28-46.

"Volatile constituents from the leaves, fruits (berries), stems and roots of Solanum xanthocarpum Schrad. & J.C. Wendl. from Nepal." Satyal, P.; Maharjan, S.; Setzer, W.N. Natural Product Communications, 2015, 10(1), 153-156.

"Radical-scavenging and antioxidant activities of essential oil components – An experimental and computational investigation." Sharopov, F.S.; Wink, M.; Setzer, W.N. Natural Product Communications, 2015, 10, 153-156.

"Essential oil compositions of Juniperus virginiana and Pinus virginiana, two important trees in Cherokee traditional medicine." Stewart, C.D.; Jones, C.D.; Setzer, W.N. American Journal of Essential Oils and Natural Products, 2014, 2(2), 17-24.

"Composition of geranium (Pelargonium graveolens) essential oil from Tajikistan. Sharopov, F.S.; Zhang, H.; Setzer, W.N. American Journal of Essential Oils and Natural Products, 2014, 2(2), 13-16.

"Chemical composition of the essential oil from the aerial parts of Chrysanthemum cinerariifolium growing in Nepal." Shrestha, S.; Satyal, P.; Pandit, G.; Setzer, W.N. American Journal of Essential Oils and Natural Products, 2014, 2(2), 1-3.

"Chemotyping and determination of antimicrobial, insecticidal, and cytotoxic properties of wild-grown Cannabis sativa from Nepal." Satyal, P.; Setzer, W.N. Journal of Medicinally Active Plants, 2014, 3(1), 9-16.

"Chemistry and leishmanicidal activity of the essential oil from Artemisia absinthium from Cuba." Monzote, L.; Piñón, A.; Scull, R.; Setzer, W.N. Natural Product Communications, 2014, 9(12), 1799-1804.

"Interactions of antiparasitic sterols with sterol 14α-demethylase (CYP51) of human pathogens." Warfield, J.; Setzer, W.N.; Ogungbe, I.V. SpringerPlus, 2014, 3, 679.

"Antileishmanial potential of tropical rainforest plant extracts." Monzote, L.; Piñón, A.; Setzer, W.N. Medicines, 2014, 1, 32-55.

"Chemical composition and biological activity of Pulicaria vulgaris essential oil from Iran." Sharifi-Rad, J.; Miri, A.; Hoseini-Alfatemi, S.M.; Sharifi-Rad, M.; Setzer, W.N.; Hadjiakhoondi, A. Natural Product Communications, 2014, 9(11), 1633-1636.

"Antifungal activity of plant extracts against Aspergillus niger and Rhizopus stolonifer." Surapuram, V.; Setzer, W.N.; McFeeters, R.L.; McFeeters, H. Natural Product Communications, 2014, 9(11), 1603-1605.

"Essential oil composition of Caperonia palustris (L.) A. St-Hil. (Euphorbiaceae) growing in southwest Nigeria." Owolabi, M.S.; Ogundago, A.L.; Ogunwande, I.A.; Hauser, R.M.; Setzer, W.N. American Journal of Essential Oils and Natural Products, 2014, 2(1), 39-40.

"Leaf Essential Oil Compositions of Rudbeckia fulgida Aiton, Rudbeckia hirta L., and Symphyotrichum novae-angliae (L.) G.L. Nesom (Asteraceae)." Stewart, C.D.; Jones, C.D.; Setzer, W.N. American Journal of Essential Oils and Natural Products, 2014, 2(1), 36-38.

"Identification of essential oil components from Conradina canescens." Dosoky, N.S.; Stewart, C.D.; Setzer, W.N. American Journal of Essential Oils and Natural Products, 2014, 2(1), 24-28.

"Cytotoxic effect of Cuban propolis extracts on normal cells and in-vitro basal toxicity assay to estimate acute oral toxicity." Frión-Herrera, Y.; Díaz-García, A. Rodríguez-Sánchez, H.; Ruiz-Fuentes, J.L.; Monzote Fidalgo, L.; Setzer, W.N. American Journal of Essential Oils and Natural Products, 2014, 2(1), 19-23.

"An In-Silico Investigation of Anti-Chagas Phytochemicals." McCulley, S.F.; Setzer, W.N. Current Clinical Pharmacology, 2014, 9(3), 205-257.

"Leaf and bark essential oil compositions of Bursera simaruba from Monteverde, Costa Rica." Setzer, W.N. American Journal of Essential Oils and Natural Products, 2014, 1(3), 34-36.

"Antileishmanial phytochemical phenolics: Molecular docking to potential protein targets." Ogungbe, I.V.; Erwin, W.R.; Setzer, W.N. Journal of Molecular Graphics & Modelling, 2014, 48, 105-117.

"Composition of essential oil from Tagetes minuta L. and cytotoxic, antioxidant and antimicrobial activities" Ali, N.A.A.; Sharopov, F.S.; Al-kaf, A.G.; Hill, G.M.; Arnold, N.; Al-Sokari, S.S.; Setzer, W.N.; Wessjohann, L. Natural Product Communications, 2014, 9(2), 265-268.

"Volatile analysis and antimicrobial screening of the parasitic plant Cuscuta reflexa Roxb. from Nepal." Paudel, P.; Satyal, P.; Maharjan, S.; Shrestha, N.; Setzer, W.N. Natural Product Research, 2014, 28(2), 106-110.

"Chemical composition of volatiles from Opuntia littoralis, Opuntia ficus-indica, and Opuntia prolifera growing on Catalina Island, California." Wright, C.; Setzer, W.N. Natural Product Research, 2014, 28(3), 208-211.

"Phytochemical investigations of Lonchocarpus bark extracts from Monteverde, Costa Rica." Deskins, C.E.; Vogler, B.; Dosoky, N.S.; Chhetri, B.K.; Haber, W.A.; Setzer, W.N. Natural Product Communications, 2014, 9(4), 507-510.

"Antileishmanial activity of the essential oil from Bixa orellana." Monzote, L.; García, M.; Scull, R.; Cuellar A, Setzer, W.N. Phytotherapy Research, 2014, 28, 753-758.

"Essential oils: New perspectives in human health and wellness." Firenzuoli, F.; Jaitak, V.; Horvath, G.; Bassolé, I.H.N.; Setzer, W.N.; Gori, L. Evidence-Based Complementary and Alternative Medicine, 2014, ID 467363.

"The volatile constituents of Parquetina nigrescens from Southwestern Nigeria." Owolabi, M.S.; Lawal, O.A.; Hauser, R.M.; Setzer, W.N. Natural Product Communications, 2014, 9(6), 857-858.

"Accumulation of silicon in cacti native to the United States: Characterization of silica bodies and cyclic oligosiloxanes in Stenocereus thurberi, Opuntia littoralis, Opuntia ficus-indica, and Opuntia stricta. Wright, C.R.; Waddell, E.A.; Setzer, W.N. Natural Product Communications, 2014, 9(6), 873-878.

"Semi-synthesis of two nitrogen derivatives of oleanolic acid and effect on MCF-7 human breast carcinoma cells." Oyedeji, O.O.; Schode, F.O.; Oyedeji, A.O.; Gwebu, E.P.; Hill, G.M.; Setzer, W.N. Journal of Anticancer Research, 2014, 34(8), 4135-4139.

"Characterization of volatiles of necrotic Stenocereus thurberi Engelm. and Opuntia littoralis (Engelm.) Cockerell and toxicity and olfactory preference of Drosophila melanogster, Drosophila mojavensis wrigleyi, and D. mojavensis sonorensis to necrotic cactus volatiles." Wright, C.R.; Setzer, W.N. Natural Product Communications, 2014, 9(8), 1185-1192.