Publications (Last 5 years)

·         Hughes, R. and Ng, J.D. (2007).  Can small laboratories do structural genomics.  Crystal Growth and Design (In press). 

·         Ng, J.D., Stevens, R.C. and Kuhn P. (2007).  Protein crystallization in restricted geometry: advancing old ideas for modern times in structural proteomics.  Methods in Molecular Biology (In press)

·         Wilson, R.C., Hughes, R.C., Curto, E.V., Ng, J.D. and Twigg, P.D. (2007). Backbone 1H, 15N, and 13C Resonance Assignments and Secondary Structure of a Novel Protein OGL-20PT-358 from Hyperthermophile Thermococcus thioreducens  sp. nov. Molecules and Cells (In press)

·         Shaw, N., Tempel W, Chang, J., Yang, H., Cheng, C., Ng, J.D., Rose, J., Rao, Z. Wang, B.C. Liu, Z.J, (2007). Crystal structure solution of a ParB-like nuclease at atomic resolution. Proteins (in press).

·         Pikuta,E., Marsic, D., Itoh, T., Bej, A.K., Tang, J., Whitman, W., Ng, J.D., Garriott, O.K. and Hoover, R.B. (2007). Thermococcus thioreducens sp. nov., a novel hyperthermophilic, obligately sulfur-reducing archaeon from a deep-sea hydrothermal vent. J Syst Evol Microbiol. (In press)

·         Baird, J.K., Caraballo, K. and Ng, J.D.(2007).  Kinetics of protein crystallization. Book Chapter in Focus on Crystal Growth Research (Ed: G.V. Karas)  pp 173-195. (In press).

·         Ng, J.D. and Garcia-Ruiz, J.M. (2006). Counter-diffusion capillary crystallization for structural enomics. Trends in Drug Discovery (in press).

·         Caraballo, K.G., Baird, J.K. and Ng, J.D. (2006). Kinetics of Supersaturation Decay in the Crystallization of Canavalin. Crystal Growth and Design. 6:874-880.

·         Garcia-Ruiz, J.M. and Ng, J.D. (2006). Counter-diffusion capillary crystallization for high throughput applications. In Protein crystallization strategies for structural genomics (N. E. Chayen, ed) International University Line Chapter 5.

·         Wang, B. C.; Adams, M.; Dailey, H.; DeLucas, L.; Luo, M.; Rose, J.; Bunzell, R.; Dailey, T.; Habel, J.; Horanyi, P. S.; Jenney, F.; Karaveg, K.; Lee, H.-S.; Li, S.; Li, S. C.; T.; Lin, D.; Liu, Z. J.; Luan, C.-H.; Mayer, M.; Nagy, L.; Newton, M. G.; Ng, J. D.; Poole, F.; Shah, A. K.; Sugar, F. F.; Xu, H. (2005). Protein production and crystallization at SECSG - An overview. Journal of Structural and Functional Genomics. 6:233-43.

·         Liu, Z. J.; Shah, A. K.; Habel, J.; Ng, J. D.; Kataeva, I.; Xu, H.; Horanyi, P.; Yang, H.; Chang, J.; Huang, L.; Chang, S.; Tempel, W.; Chen, L.; Zhou, W.; Lee, D.; Lin, D.; Zhang, H.; Newton, G.; Rose, J.; Wang, B.-C.(2005). Salvaging Pyrococcus furiosus protein targets at SECSG. J Struct Funct Genomics 6:121-127.

·         Liu, Z. J.; Tempel, W.; Ng, J. D.; Lin, D.; Shah, A. K.; Chen, L.; Horanyi, P. S.; Habel, J.; Kataeva, I.; Xu, H.; Yang, H.; Chang, J. C.; Huang, L.; Chang, S.; Zhou, W.; Lee, D.; Praissman, J.; Zhang, H.; Newton, M. G.; Rose, J. P.; Richardson, J. S.; Richardson, D. C.; Wang, B.-C.(2005). The High Throughput Protein to Structure Pipeline at SECSG. Acta Crystallogr D Biol Crystallogr 61:679-84.

·         Bernhardsdotter, E.C.M.J., Ng, J.D., Garriott, O.K. and Pusey, M.L. (2005). Enzymatic properties of an alkaline chelator resistant a-amylase form an alkaliphilic Bacillus sp. Isolate L1711. Process Biochemistry 40:2401-2408.

·         Pusey, M.L., Liu, Z-J, Tempel, W., Praissman, J., Lin, D., Wang, B-C., Gavira, J.A. and Ng, J.D. (2005).  Life in the fast lane for protein crystallization and X-ray crystallography.  Progress in Biophysics and Molecular Biology 88:359-386.

·         Ng, J.D. (2004). DNA to protein and perspectives on protecting the fruits of structural genomic research. Journal of International Law 1: 40-42.

·         Ng, J.D., Gavira, J.A. and Garcia-Ruiz MA. (2003). Protein crystallization by capillary counter-diffusion for applied crystallographic structure determination. Journal of Structural Biology 142:218-231.

·         Ng, J.D. (2002). Space grown crystals are more useful for structure determination. Annals of the New York Academy of Sciences 974:598-609.

·         de la Rosa, A. P., Ng, J., Day, J. and McPherson, A. (2003) Structural characterization of satellite tobacco mosaic virus RNA. Agrocienda 37, 503-510.

·         Lorber, B., Theobald-Dietrich, A., Charron, C., Sauter, C. Ng, J.D., Zhu, D.W. and Giege, R. (2002). From conventional crysatllization to better crystals from space: a review on pilot cryatllogenesis studies with aspartyl-tRNA synthetases. Acta Crystallographica D58: 1674-1680

·         Gavira, J.A., Lopéz-Jaramillo, J., Toh, D., Garcia-Ruiz, J.M. and Ng, J.D. (2002). Ab initio crystallographic structure determination of insulin form protein to electron density without crystal handling. Acta Crystallogr D58 :1085-1254

·         Ng, J.D., Sauter, C., Lorber, B., Kirkland, N., Arnez, J. and Giegé, R. (2002). Comparative analysis of space- and earth-grown crystals of an aminoacy-tRNA synthetase: Space-grown crystals are more useful for structural determination. Acta Crystallographica Section D. D58:645-652

·         Hoover, R.B., Pikuta, E. V., Marsic, D. and Ng, J.D. (2001). Anaerobic Psychrophiles from Alaska, Antarctica, and Patagonia: Implications to Possible Life on Mars and Europa. Proceedings to the International Society for Optical Engineering: Instruments, Methods and Missions for Astrobiology II . 4495:313.

·         Marsic, D., Pikuta, E.V., Hoover, R. and Ng, J.D. (2001). Cloning of the 16S ribosomal RNA gene of a psychrophilic bacterium from the Alaskan Fox Permafrost Tunnel. Proceedings to the International Society for Optical Engineering: Instruments, Methods and Missions for Astrobiology II . 3755:163-173.

·         Green, M.E., Kirkland, N. and Ng, J.D. (2001). Effect of a mutation at arginine 301 on the stability, crystal quality and the preliminary crystallographic analysis of recombinant canavalin from Canavalia ensiformis. J. Cryst. Growth 232:387-398.

·         Charron, C., Sauter, C., Zhu, D.W., Ng, J.D. Kern, Lorber,B. and Giegé, R. (2001). Packing contacts in orthorhombic and monoclinic crystals of a thermophilic aspartyl-tRNA synthetase favor the hydrophobic regions of the protein. J. Cryst. Growth 232: 376-386.

·         Zhu, D.W., Lorber, B., Sauter, C., Ng, J.D., Benas, P., Le Grimellec, C. and Giege, R. (2001). Growth kinetics, diffraction properties, and effect of agarose on the stability of a novel crystal form of T. thermophilus aspartyl-tRNA synthetase-1 Acta Crystallographica Section D. Acta Cryst. D57, 552-558.

·         Roberts, P.H., Zhou, X., Holmes, A., Ranson, H., Small, G., Hemingway, J., Ng, J.D., Chen, L. and Meehan, E.J. (2001). Multi-form crystallization of agGST1-6, a recombinant glutathione S-transferase from a DDT-Resistant strain of Anopheles gambiae. Acta Crystallographica Section D57:134-136.

Complete publications are listed in Curriculum vitae