UAH

William N. Setzer

setzer w

Chair, Department of Chemistry
Professor, Organic Chemistry

Adjunct Professor, Biological Sciences

Office: MSB 115
Phone: 256.824.6519
Fax: 256.824.6349
Email: wsetzer@chemistry.uah.edu

Résumé

Research Interests

My current research interests are concerned with secondary metabolites of higher plants; biomedicinal aspects of biologically active phytochemicals and chemical ecology.

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Selected Publications

“Accumulation of silicon in cacti native to the United States:  Characterization of silica bodies and cyclic oligosiloxanes in Stenocereus thurberi, Opuntia littoralis, Opuntia ficus-indica, and Opuntia stricta.  Wright, C.R.; Waddell, E.A.; Setzer, W.N.  Natural Product Communications, 2014, 9(6), 873-878.

“The volatile constituents of Parquetina nigrescens from Southwestern Nigeria.”  Owolabi, M.S.; Lawal, O.A.; Hauser, R.M.; Setzer, W.N.  Natural Product Communications, 2014, 9(6), 857-858.

“Essential oils:  New perspectives in human health and wellness.”  Firenzuoli, F.; Jaitak, V.; Horvath, G.; Bassolé, I.H.N.; Setzer, W.N.; Gori, L.  Evidence-Based Complementary and Alternative Medicine, 2014, ID 467363.

“Antileishmanial activity of the essential oil from Bixa orellana.”  Monzote, L.; García, M.; Scull, R.; Cuellar A, Setzer, W.N.  Phytotherapy Research, 2014, 28, 753-758.

“Phytochemical investigations of Lonchocarpus bark extracts from Monteverde, Costa Rica.”  Deskins, C.E.; Vogler, B.; Dosoky, N.S.; Chhetri, B.K.; Haber, W.A.; Setzer, W.N.  Natural Product Communications, 2014, 9(4), 507-510.

“Chemical composition of volatiles from Opuntia littoralis, Opuntia ficus-indica, and Opuntia prolifera growing on Catalina Island, California.”  Wright, C.; Setzer, W.N.  Natural Product Research, 2014, 28(3), 208-211.

“Volatile analysis and antimicrobial screening of the parasitic plant Cuscuta reflexa Roxb. from Nepal.”  Paudel, P.; Satyal, P.; Maharjan, S.; Shrestha, N.; Setzer, W.N.  Natural Product Research, 2014, 28(2), 106-110.

“Composition of essential oil from Tagetes minuta L. and cytotoxic, antioxidant and antimicrobial activities”  Ali, N.A.A.; Sharopov, F.S.; Al-kaf, A.G.; Hill, G.M.; Arnold, N.; Al-Sokari, S.S.; Setzer, W.N.; Wessjohann, L.  Natural Product Communications, 2014, 9(2), 265-268.

“Antileishmanial phytochemical phenolics:  Molecular docking to potential protein targets.”  Ogungbe, I.V.; Erwin, W.R.; Setzer, W.N.  Journal of Molecular Graphics & Modelling, 2014, 48, 105-117.

“Leaf and bark essential oil compositions of Bursera simaruba from Monteverde, Costa Rica.”  Setzer, W.N.  American Journal of Essential Oils and Natural Products, 2014, 1(3), 34-36.

“Volatile components of organ pipe cactus, Stenocereus thurberi Engelm., growing in the Organ Pipe Cactus National Monument and the Arizona-Sonora Desert Museum.”  Wright, C.R.; Setzer, W.N.  American Journal of Essential Oils and Natural Products, 2013, 1(3), 19-22.

“Chemical composition of the floral essential oil of Tabernaemontana longipes from Monteverde, Costa Rica.”  Setzer, W.N.  American Journal of Essential Oils and Natural Products, 2013, 1(3), 16-18.

“Chemical composition of the leaf essential oil of Clibadium leiocarpum from Monteverde, Costa Rica.”  Washington, V.D.; Agius, B.R.; Palazzo, M.C.; Haber, W.A.; Setzer, W.N.  American Journal of Essential Oils and Natural Products, 2013, 1(2), 43-45.

“The floral essential oil composition of Albizia julibrissin growing in northern Alabama.”  Zhang, H.; Setzer, W.N.  American Journal of Essential Oils and Natural Products, 2013, 1(2), 41-42.

“Chemical composition of the leaf essential oil of an undescribed species of Zanthoxylum from Monteverde, Costa Rica.” Miller, S.L.; Haber, W.A.; Setzer, W.N.  American Journal of Essential Oils and Natural Products, 2013, 1(2), 38-40.

“Bioactivities and compositional analyses of Cinnamomum essential oils from Nepal:  C. camphora, C.tamala,and C. glaucescens.”  Satyal, P.; Paudel, P.; Poudel, A.; Dosoky, N.S.; Pokharel, K.K.; Setzer, W.N.  Natural Product Communications, 2013, 8(12), 1777-1784.

“Tropical protozoan diseases:  Natural product drug discovery and development.”  Muschietti, L.; Vila, R.; Filho, V.C.; Setzer, W.N.  Evidence-Based Complementary and Alternative Medicine, 2013, ID 404250.

“Bioactivities and compositions of Betula nigra essential oils.”  Woods, K.E.; Chhetri, B.K.; Jones, C.D.; Goel, N.; Setzer, W.N.  Journal of Medicinally Active Plants, 2013, 2(1), 1-9.

“Interactions of antiparasitic alkaloids with Leishmania protein targets:  A molecular docking analysis.”  Ogungbe, I.V.; Ng, J.D.; Setzer, W.N.  Future Medicinal Chemistry, 2013, 5(15), 1777-1799.

“Trypanosomatid disease drug discovery and target identification.”  Setzer, W.N.  Future Medicinal Chemistry, 2013, 5(15), 1703-1704.

Juglans regia and Juglans nigra, two trees important in traditional medicine:  A comparison of leaf essential oil compositions and biological activities.”  Paudel, P.; Satyal, P.; Dosoky, N.S.; Maharjan, S.; Setzer, W.N.  Natural Product Communications, 2013, 8(10), 1481-1486.

“Cytotoxic effect of Cuban propolis extracts against tumor cell lines.”  Frión-Herrera, Y.; Díaz-García, A.; Rodriguez-Sánchez, H.; Ruiz-Fuentes, J.; Monzote-Fidalgo, L.; Morier-Díaz, L.; Setzer, W.N.  American Journal of Essential Oil and Natural Products, 2013, 1(1), 112-117.

“Chemical composition of the leaf essential oil of Terminalia catappa L. growing in southwestern Nigeria.”  Owolabi, M.S.; Lawal, O.A.; Ogunwande, I.A.; Hauser, R.M.; Setzer, W.N.  American Journal of Essential Oils and Natural Products, 2013, 1(1), 51-54.

“1-Nitro-2-phenylethane dominates the chemical composition of the leaf essential oil of Uvaria chamae from Badary, Nigeria.”  Owolabi, M.S.; Adewale, O.R.; Dosoky, N.S.; Setzer, W.N.  American Journal of Essential Oils and Natural Products, 2013, 1(1), 48-50.

“Volatile compositions of two cactus species growing in the Sonoran Desert of southern Arizona.”  Wright, C.R.; Setzer, W.N.  American Journal of Essential Oils and Natural Products, 2013, 1(1), 41-47.

“Aroma chemical composition of Piper guineense Schumach. & Thonn. from Lagos, Nigeria:  A new chemotype.”  Owolabi, M.S.; Lawal, O.A.; Ogunwande, I.A.; Hauser, R.M.; Setzer, W.N.  American Journal of Essential Oils and Natural Products, 2013, 1(1), 37-40.

“The leaf essential oil of Momordica charantia from Nigeria is dominated by geijerene and pregeijerene.”  Owolabi, M.S.; Omikorede, O.E.; Yusuf, K.A.; Paudel, P.; Setzer, W.N.  Journal of Essential Oil-Bearing Plants, 2013, 16(3), 377-381.

“Chemical composition and phytotoxicity of the essential oil of Encelia farinosa growing in the Sonoran Desert.”  Wright, C.; Chhetri, B.K.; Setzer, W.N.  American Journal of Essential Oil and Natural Products, 2013, 1(1), 18-22.

“Leaf oil composition of Croton zambesicus Muell. Arg. growing in southwestern Nigeria:  Essential oil chemotypes of C. zambesicus.”  Owolabi, M.S.; Oladipupo, L.A.; Lajide, L.; Hauser, R.M.; Setzer, W.N.  American Journal of Essential Oils and Natural Products, 2013, 1(1), 14-17.

“Chemical compositions, phytotoxicity, and biological activities of Acorus calamus essential oils from Nepal.”  Satyal, P.; Paudel, P.; Poudel, A.; Dosoky, N.S.; Moriarity, D.M.; Setzer, W.N.  Natural Product Communications, 2013, 8(8), 1179-1181.

“Composition and antiproliferative activity of the essential oil of Galagania fragrantissima Lipsky (Apiaceae).”  Sharopov, F.S.; Wink, M.; Khalifaev, D.R.; Zhang, H.; Dosoky, N.S.; Setzer, W.N.  American Journal of Essential Oil and Natural Products, 2013, 1, 11-13.

“Chemical composition, antimicrobial, and cytotoxic assessment of Mitracarpus scaber Zucc. (Rubiaceae) essential oil from southwestern Nigeria.”  Owolabi, M.S.; Lawal, O.A.; Dosoky, N.S.; Satyal, P.; Setzer, W.N.  American Journal of Essential Oil and Natural Products, 2013, 1, 4-6.

“The cytotoxic activity of Annona muricata leaf oil from Badagary, Nigeria.”  Owolabi, M.S.; Ogundajo, A.L.; Dosoky, N.S.; Setzer, W.N.  American Journal of Essential Oil and Natural Products, 2013, 1, 1-3.

“Composition and bioactivities of leaf essential oil of Cassia tora.”  Satyal, P.; Mallik, S.; Gautam, T.; Vogler, B.; Setzer, W.N.  Chemistry of Natural Compounds, 2013, 49, 553-554.

In-silico Leishmania target selectivity by antiparasitic terpenoids.”  Ogungbe, I.V.; Setzer, W.N.  Molecules, 2013, 18, 7761-7847 (Special Issue, Plant Natural Products against Human Parasites).

“Composition and bioactivity of the essential oil of Anethum graveolens from Tajikistan.”  Sharopov, F.S.; Wink, M.; Gulmurodov, I.S.; Zhang, H.; Setzer, W.N.  International Journal of Medicinal and Aromatic Plants, 2013, 3(2), 125-130.

“Antimicrobial, antioxidant, and cytotoxic activities of the essential oil of Tarchonanthus camphoratus L.”  Ali, N.A.A.; Al-Fatimi, M.A.; Crouch, R.A.; Setzer, W.N.; Wessjohann, L.  Natural Product Communications, 2013, 8(5), 683-686.

“Antioxidant and antihemolytic activity of lipid-soluble bioactive substances from avocado fruits.”  Nabavi, S.F.; Nabavi, S.M.; Setzer, W.N.; Nabavi, S.A.; Nabavi, S.A.; Ebrahmzadeh, M.A.  Fruits, 2013, 68(3), 185-193.

“Composition and bioactivity of the essential oil of Melissa officinalis L. growing wild in Tajikistan.”  Sharopov, F.S.; Wink, M.; Khalifaev, D.R.; Zhang, H.; Dosoky, N.S.; Setzer, W.N.  International Journal of Traditional and Natural Medicines, 2013, 2(2), 86-96.

“Pharmacological activities of basil oil:  A review.”  Ali, N.A.A.; Setzer, W.N.  Recent Progress in Medicinal Plants, Vol. 37 “Essential Oils of Medicinal Importance”, 2013, 37, 286-307.

“Volatile constituents of Pinus roxburghii from Nepal.”  Satyal, P.; Paudel, P.; Raut, J.; Deo, A.; Dosoky, N.S.; Setzer, W.N.  Pharmacognosy Research, 2013, 5, 43-48.

“The leaf essential oil composition of Eugenia javanica from southwest Nigeria and insecticidal activity against Sitophilus zeamais.  Owolabi, M.S.; Kazeem, W.; Dosoky N.S.; Setzer, W.N.  African Journal of Plant Science and Biotechnology, 2013, 7, 86-88.